HitPredict

Interactor 1: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29509190
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1068 Hs			1 530
+	Hs
		369763 CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1189781 MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		993279 ACTN3_HUMAN (960-1066): 1.62e-47: 186: 39.82		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369901 MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		865150 SMTN_HUMAN (750-1067): 9.99e-35: 145: 22.26		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		521591 ACTN1_HUMAN (960-1067): 7.16e-33: 139: 40.37		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269900 MYH13_HUMAN (221-985): 2.46e-30: 132: 10.64		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		724944 MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368902 MYH6_HUMAN (148-986): 1.44e-34: 146: 9.91		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369966 MILK2_HUMAN (962-1066): 5.25e-33: 140: 37.74		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		522631 MYH7_HUMAN (1-526): 4.38e-18: 92.6: 8.26		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		368893 ACTN1_HUMAN (960-1067): 7.16e-33: 139: 40.37		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		1270044 MYH4_HUMAN (2-423): 3.1e-15: 83.4: 9.93		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369096 MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Mm
		1142708 SMTN_MOUSE (730-1067): 6.96e-37: 152: 22.22		ERR2_MOUSE (69-499): 5.26e-107: 328: 31.11
+	Hs
		587127 MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		521532 ACTN1_HUMAN (960-1067): 7.16e-33: 139: 40.37		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		487552 MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487183 MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Mm
		580490 ACTN2_MOUSE (963-1066): 3.87e-15: 82.4: 40.95		ANDR_MOUSE (149-407): 1.53e-38: 152: 33.70