HitPredict

Interactor 1: CDKL4 (Q5MAI5)
Cyclin-dependent kinase-like 4 (EC 2.7.11.22)
Gene: CDKL4

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 379 Hs			1 2054
+	Hs
		625530 CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76		MY18A_HUMAN (1-2054): 0: 1279: 100.00
+	Hs
		528401 CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76		MYH8_HUMAN (1116-1997): 2.71e-53: 209: 14.76
+	Hs
		960129 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH13_HUMAN (1051-1986): 4.14e-54: 212: 13.75
+	Hs
		528405 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH8_HUMAN (1116-1997): 2.71e-53: 209: 14.76
+	Hs
		528368 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH6_HUMAN (1141-2053): 1.27e-51: 204: 13.34
+	Hs
		502908 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH3_HUMAN (1134-2052): 4.44e-51: 202: 15.52
+	Hs
		625176 CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		522604 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH7_HUMAN (954-1819): 2.95e-41: 169: 12.80
+	Hs
		522542 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH1_HUMAN (959-1794): 5.17e-37: 156: 9.50
+	Hs
		960128 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH2_HUMAN (1056-1724): 7.97e-34: 145: 11.11
+	Hs
		625177 CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		625654 CDK2_HUMAN (1-292): 3.58e-140: 402: 37.76		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84
+	Hs
		1026889 MK07_HUMAN (2-365): 5.34e-131: 396: 24.80		MYO5B_HUMAN (1603-2051): 4.65e-14: 80.6: 9.19
+	Hs
		1026895 MK07_HUMAN (2-365): 5.34e-131: 396: 24.80		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84
+	Hs
		960130 CDK3_HUMAN (1-297): 3.87e-138: 397: 39.47		MYH15_HUMAN (1248-1834): 8.79e-09: 63.2: 18.86
+	Hs
		724717 CDK7_HUMAN (2-288): 1.63e-62: 205: 38.87		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		725114 CDK7_HUMAN (2-288): 1.63e-62: 205: 38.87		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56