HitPredict

Interactor 1: DIRA2 (Q5PR73)
GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2)
Gene: Diras2

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30562941
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 199 Mm			1 817
+	Mm
		918987 RAB1A_MOUSE (2-197): 2.07e-82: 244: 29.70		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		1164014 RAB14_MOUSE (3-196): 4.84e-76: 228: 23.22		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Mm
		895596 RAB8B_MOUSE (4-199): 9.03e-76: 228: 26.83		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Hs
		914039 RB11A_HUMAN (3-197): 2.29e-77: 232: 26.79		DLG1_HUMAN (80-763): 3.75e-33: 139: 11.22
+	Mm
		1143458 RAB14_MOUSE (3-196): 4.84e-76: 228: 23.22		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		919668 RAP1A_HUMAN (7-173): 2.97e-46: 152: 45.83		RADIL_HUMAN (176-582): 1.35e-44: 176: 18.05
+	Dm
		442954 RAP1_DROME (7-166): 1.6e-44: 147: 45.00		Q24279_DROME (479-617): 7.55e-45: 177: 35.25
+	Dm
		442967 RAP1_DROME (7-166): 1.6e-44: 147: 45.00		Q95TT5_DROME (479-617): 1.11e-44: 177: 35.25
+	Hs
		876348 RAP1A_HUMAN (7-173): 2.97e-46: 152: 45.83		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		318121 DIRA3_HUMAN (7-199): 1.36e-52: 169: 48.45		DLG1_HUMAN (80-763): 3.75e-33: 139: 11.22
+	Dm
		442960 RAP1_DROME (7-166): 1.6e-44: 147: 45.00		Q8IPP3_DROME (479-613): 8.32e-40: 161: 34.07
+	Dm
		332213 O96692_DROME (20-166): 3.05e-37: 129: 44.22		Q95TT5_DROME (479-617): 1.11e-44: 177: 35.25
+	Dm
		332203 O96692_DROME (20-166): 3.05e-37: 129: 44.22		Q8IPP3_DROME (479-613): 8.32e-40: 161: 34.07
+	Hs
		486019 RAP2A_HUMAN (7-166): 2.7e-37: 129: 51.25		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		876485 RIT2_HUMAN (5-186): 4.19e-33: 119: 35.71		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Hs
		876463 RIT1_HUMAN (5-172): 9.77e-33: 118: 36.91		AFAD_HUMAN (397-798): 1.76e-38: 157: 18.69
+	Mm
		897997 RAP2B_MOUSE (7-166): 2.29e-40: 137: 49.38		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		318119 DIRA3_HUMAN (7-199): 1.36e-52: 169: 48.45		PTN13_HUMAN (51-808): 7.26e-17: 88.2: 9.60
+	Hs
		318190 DIRA3_HUMAN (7-199): 1.36e-52: 169: 48.45		DLG5_HUMAN (424-594): 7.08e-09: 62: 18.75