Interactor 1: ESPL1 (Q14674)
Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)
Gene: ESPL1
Interactor 2: UBP21 (Q9UK80)
Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21)
Gene: USP21
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.55 | 0.480 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22626734 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006508 - proteolysis GO:0008234 - cysteine-type peptidase activity |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
