Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: DGCR8 (Q8WYQ5)
Microprocessor complex subunit DGCR8 (DiGeorge syndrome critical region 8)
Gene: DGCR8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.55 0.559

The method score is based on:

Property Details
Experiments 29656893, 34188037
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
GO:0016604 - nuclear body
GO:0035861 - site of double-strand break
Homologous interactions 0

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Last updated: 11Aug2025