HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: AN32B (Q92688)
Acidic leucine-rich nuclear phosphoprotein 32 family member B (Acidic protein rich in leucines) (Putative HLA-DR-associated protein I-2) (PHAPI2) (Silver-stainable protein SSP29)
Gene: ANP32B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31046837, unassigned1853
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2527 Hs			1 251
+	Hs
		453839 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		RU2A_HUMAN (5-173): 3.1e-42: 146: 26.63
+	Hs
		1130525 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		AN32E_HUMAN (1-153): 8.79e-38: 135: 66.01
+	Hs
		1130680 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		CEP72_HUMAN (14-251): 3.63e-32: 125: 16.46
+	Hs
		2885 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A0A0G2JPP5_HUMAN (54-251): 2.06e-13: 71.5: 13.64
+	At
		1114719 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		TMM_ARATH (14-188): 1.07e-26: 109: 18.03
+	At
		1114706 ERECT_ARATH (786-1617): 1.51e-156: 514: 16.41		PXL1_ARATH (4-174): 5.88e-18: 84.6: 18.69
+	At
		248983 PEPR2_ARATH (820-1589): 5.79e-139: 467: 13.81		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	At
		249011 BRL1_ARATH (792-1496): 3.09e-132: 449: 15.92		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	At
		84735 Y4361_ARATH (994-1657): 1.78e-103: 363: 15.21		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	At
		83970 Y1743_ARATH (883-1624): 7.49e-103: 360: 14.17		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	Zm
		111843 K7V4X2_MAIZE (795-1429): 1.29e-103: 363: 14.69		K7V4X2_MAIZE (18-178): 7.22e-09: 58: 21.05
+	At
		248972 CEPR2_ARATH (921-1445): 3.86e-88: 313: 17.38		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	At
		1325020 PXL1_ARATH (1880-2156): 1.5e-71: 264: 21.20		PXL1_ARATH (4-174): 5.88e-18: 84.6: 18.69
+	At
		221758 BAME1_ARATH (1119-1672): 2.48e-71: 263: 13.35		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	At
		85379 ERL1_ARATH (1221-1692): 2.02e-59: 226: 13.31		TMM_ARATH (14-188): 1.07e-26: 109: 18.03
+	At
		85103 ERL2_ARATH (1183-1706): 5.31e-63: 237: 12.75		RGI2_ARATH (32-183): 1.86e-17: 83.4: 17.51
+	Hs
		1327208 MFHA1_HUMAN (838-1119): 1.5e-30: 134: 16.95		DRC3_HUMAN (5-219): 5.35e-36: 135: 23.72
+	At
		1325025 BRL3_ARATH (780-1151): 1.32e-42: 174: 12.21		PXL1_ARATH (4-174): 5.88e-18: 84.6: 18.69
+	At
		248958 SKM1_ARATH (1899-2133): 1.84e-29: 130: 18.25		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29
+	At
		249009 BRL2_ARATH (1470-1771): 1.68e-09: 65.8: 10.33		O64794_ARATH (70-222): 1.88e-14: 74.2: 14.29