HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: CALL5 (Q9NZT1)
Calmodulin-like protein 5 (Calmodulin-like skin protein)
Gene: CALML5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	24725412
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 146
+	At
		99010 RGI4_ARATH (1221-2146): 2.44e-86: 310: 14.84		CALM7_ARATH (1-146): 3.23e-49: 156: 45.64
+	At
		99011 RGI4_ARATH (1221-2146): 2.44e-86: 310: 14.84		CALM6_ARATH (1-146): 4.68e-49: 156: 45.64
+	At
		483179 CRK40_ARATH (1878-2162): 3.33e-85: 296: 29.28		CALM4_ARATH (1-146): 2.43e-49: 156: 46.31
+	At
		886640 CRK40_ARATH (1878-2162): 3.33e-85: 296: 29.28		CALM7_ARATH (1-146): 3.23e-49: 156: 45.64
+	At
		976701 CRK40_ARATH (1878-2162): 3.33e-85: 296: 29.28		CALM6_ARATH (1-146): 4.68e-49: 156: 45.64
+	At
		1104952 PXL1_ARATH (1880-2156): 1.5e-71: 264: 21.20		CDPK5_ARATH (1-145): 5.04e-47: 161: 35.37
+	At
		99008 RGI4_ARATH (1221-2146): 2.44e-86: 310: 14.84		CML10_ARATH (1-143): 8.31e-29: 105: 40.56
+	At
		99003 RGI4_ARATH (1221-2146): 2.44e-86: 310: 14.84		CML8_ARATH (5-143): 6.15e-28: 102: 42.25
+	At
		672620 CRK40_ARATH (1878-2162): 3.33e-85: 296: 29.28		CML10_ARATH (1-143): 8.31e-29: 105: 40.56
+	At
		188365 CRK40_ARATH (1878-2162): 3.33e-85: 296: 29.28		CML8_ARATH (5-143): 6.15e-28: 102: 42.25
+	At
		626405 Y1343_ARATH (1868-2199): 8.91e-89: 312: 26.74		CML12_ARATH (4-98): 5.4e-09: 55.1: 30.53
+	At
		99007 RGI4_ARATH (1221-2146): 2.44e-86: 310: 14.84		CML12_ARATH (4-98): 5.4e-09: 55.1: 30.53
+	At
		626403 CRK40_ARATH (1878-2162): 3.33e-85: 296: 29.28		CML12_ARATH (4-98): 5.4e-09: 55.1: 30.53
+	At
		989500 CLV1_ARATH (1161-1721): 1.59e-67: 251: 13.64		CDPK1_ARATH (4-84): 1.57e-11: 62.5: 28.05
+	Hs
		648644 MFHA1_HUMAN (838-1119): 1.5e-30: 134: 16.95		CALL3_HUMAN (1-146): 8.79e-50: 158: 45.64
+	Zm
		28109 A0A1D6JP61_MAIZE (1833-2136): 1.66e-24: 114: 29.18		B4FY36_MAIZE (5-143): 1.39e-25: 97.1: 40.85