HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: PA2G4 (Q9UQ80)
Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1)
Gene: PA2G4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31046837
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome GO:1990904 - ribonucleoprotein complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 394
+	Hs
		985658 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		Q05D08_HUMAN (4-367): 1.89e-144: 418: 97.25
+	Hs
		840963 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		MAP2_HUMAN (2-336): 2.64e-110: 333: 22.71
+	Hs
		862947 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		MAP11_HUMAN (1-269): 1.11e-92: 285: 14.03
+	Hs
		3581 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A0A140VJR2_HUMAN (3-271): 8.37e-59: 200: 11.80
+	Hs
		201467 M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83		PA2G4_HUMAN (1-394): 1.74e-154: 443: 100.00