HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: V9HWE1 (V9HWE1)
Vimentin
Gene: HEL113

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0010977 - negative regulation of neuron projection development GO:0030424 - axon
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 466
+	Hs
		409102 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51
+	Hs
		443567 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		VIME_HUMAN (14-466): 9.64e-116: 349: 100.00
+	Hs
		1130283 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C73_HUMAN (5-414): 3.57e-91: 289: 32.10
+	Hs
		72923 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DN72_HUMAN (4-418): 3.99e-90: 284: 31.98
+	Hs
		422196 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		NFL_HUMAN (82-413): 4.58e-87: 278: 51.80
+	Hs
		61511 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A5YM63_HUMAN (9-412): 7.81e-83: 275: 46.44
+	Hs
		380486 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C6B_HUMAN (68-430): 5.13e-73: 242: 33.42
+	Hs
		531584 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		K2C5_HUMAN (68-414): 4.76e-72: 240: 34.66
+	Hs
		3119 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		A0A0S2Z428_HUMAN (68-430): 1.62e-71: 238: 32.88