HitPredict

Interactor 1: GRDN (Q5SNZ0)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: Ccdc88a

Interactor 2: AKT2 (Q60823)
RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-2) (Protein kinase B beta) (PKB beta) (RAC-PK-beta)
Gene: AKT2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15753085
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005080 - protein kinase C binding GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1873 Mm			1 481
+	Mm
		682109 GRDN_MOUSE (1-1873): 1.14e-158: 536: 100.00		AKT1_MOUSE (1-478): 0: 566: 82.05
+	Hs
		681881 GRDN_HUMAN (1-1873): 3.8e-156: 529: 94.77		AKT1_HUMAN (1-478): 0: 563: 81.84
+	Hs
		568689 GRDN_HUMAN (1-1873): 3.8e-156: 529: 94.77		KAPCA_HUMAN (115-446): 3.9e-146: 423: 37.95
+	Hs
		681696 MYH9_HUMAN (946-1706): 9.55e-24: 112: 10.56		AKT1_HUMAN (1-478): 0: 563: 81.84
+	Hs
		551616 DESP_HUMAN (267-1192): 2.38e-09: 65.1: 19.79		AKT1_HUMAN (1-478): 0: 563: 81.84
+	Hs
		116964 MYH1_HUMAN (706-1867): 1.28e-34: 148: 8.83		SGK1_HUMAN (104-478): 2.14e-148: 432: 45.77
+	Mm
		554901 MYH6_MOUSE (987-1770): 1.43e-31: 138: 10.49		KPCE_MOUSE (41-475): 2.95e-148: 442: 36.99
+	Hs
		610795 MYH2_HUMAN (706-1867): 9.61e-36: 151: 9.00		KAPCB_HUMAN (115-445): 4.48e-145: 420: 39.28
+	Hs
		522538 MYH1_HUMAN (706-1867): 1.28e-34: 148: 8.83		KAPCB_HUMAN (115-445): 4.48e-145: 420: 39.28
+	Mm
		554927 MYH7_MOUSE (23-813): 3.24e-27: 123: 11.39		KPCE_MOUSE (41-475): 2.95e-148: 442: 36.99
+	Hs
		724784 MYH9_HUMAN (946-1706): 9.55e-24: 112: 10.56		KPCE_HUMAN (58-475): 3.12e-148: 442: 38.96
+	Hs
		568568 MYH10_HUMAN (40-704): 2.88e-29: 130: 14.72		KAPCA_HUMAN (115-446): 3.9e-146: 423: 37.95
+	Dm
		397193 MYSN_DROME (858-1511): 7.86e-22: 106: 12.23		KPC1_DROME (119-478): 3.37e-147: 438: 41.27
+	Hs
		528359 MYH6_HUMAN (1001-1797): 9.3e-27: 122: 10.35		KAPCB_HUMAN (115-445): 4.48e-145: 420: 39.28
+	Hs
		610802 MYH4_HUMAN (978-1718): 7.99e-27: 122: 11.45		KAPCB_HUMAN (115-445): 4.48e-145: 420: 39.28
+	Hs
		568567 MYH9_HUMAN (946-1706): 9.55e-24: 112: 10.56		KAPCA_HUMAN (115-446): 3.9e-146: 423: 37.95
+	Hs
		518814 TPR_HUMAN (4-542): 2.74e-19: 97.8: 10.13		KAPCA_HUMAN (115-446): 3.9e-146: 423: 37.95
+	Hs
		551672 DESP_HUMAN (267-1192): 2.38e-09: 65.1: 19.79		KPCE_HUMAN (58-475): 3.12e-148: 442: 38.96
+	Hs
		518859 TPR_HUMAN (4-542): 2.74e-19: 97.8: 10.13		KPCZ_HUMAN (149-475): 3.63e-100: 314: 45.24