HitPredict

Interactor 1: CYFP2 (Q5SQX6)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: Cyfip2

Interactor 2: ABI1 (Q8CBW3)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	28671696, 32560809, 20697350
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Abi_HHR~FragX_IP
Common GO terms	GO:0005634 - nucleus GO:0031209 - SCAR complex GO:0043005 - neuron projection
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1253 Mm			1 481
+	Hs
		1224632 CYFP2_HUMAN (1-1253): 0: 2126: 97.97		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Mm
		1186395 CYFP1_MOUSE (1-1252): 0: 2041: 87.31		ABI1_MOUSE (1-481): 7.25e-118: 356: 100.00
+	Mm
		913886 CYFP2_MOUSE (1-1253): 0: 2134: 100.00		ABI2_MOUSE (1-481): 1.24e-81: 261: 65.78
+	Hs
		1184628 CYFP1_HUMAN (1-1252): 0: 2048: 87.55		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		1290809 CYFP2_HUMAN (1-1253): 0: 2126: 97.97		ABI2_HUMAN (1-481): 2.09e-72: 239: 61.79
+	Mm
		1131085 CYFP2_MOUSE (1-1253): 0: 2134: 100.00		AMPH_MOUSE (3-476): 5.67e-41: 157: 12.85
+	Hs
		1184662 CYFP1_HUMAN (1-1252): 0: 2048: 87.55		ABI2_HUMAN (1-481): 2.09e-72: 239: 61.79
+	Mm
		1131060 CYFP2_MOUSE (1-1253): 0: 2134: 100.00		SRC8_MOUSE (261-475): 6.43e-34: 136: 19.64
+	Hs
		1290813 CYFP2_HUMAN (1-1253): 0: 2126: 97.97		ABI3_HUMAN (276-475): 6.49e-15: 78: 24.04
+	Dm
		1365310 CYFIP_DROME (1-1252): 0: 1908: 66.02		Q9Y0S9_DROME (1-477): 6.31e-70: 232: 35.98