HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 2346
+	Mm
		1149129 CE170_MOUSE (1-1584): 0: 592: 88.00		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Mm
		1193510 C170B_MOUSE (1-1560): 8.79e-109: 383: 28.19		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Hs
		1131834 CE170_HUMAN (1-1584): 0: 654: 100.00		CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73
+	Hs
		1138297 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		166721 CE170_HUMAN (1-1584): 0: 654: 100.00		CE290_HUMAN (10-915): 3.83e-20: 100: 9.92
+	Hs
		1131818 CE170_HUMAN (1-1584): 0: 654: 100.00		CK5P2_HUMAN (1-1501): 2.27e-17: 91.6: 8.90
+	Hs
		1131826 CE170_HUMAN (1-1584): 0: 654: 100.00		AKAP9_HUMAN (196-822): 2.21e-10: 68.9: 11.25
+	Mm
		1194548 TARA_MOUSE (659-1549): 4.78e-15: 83.3: 10.80		MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33
+	Hs
		1296682 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73
+	Hs
		724700 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Hs
		725013 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Hs
		1296675 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		AKAP9_HUMAN (196-822): 2.21e-10: 68.9: 11.25
+	Hs
		551790 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Dm
		404245 TITIN_DROME (148-1536): 1.72e-09: 65.1: 8.19		MYSA_DROME (29-785): 1.4e-23: 112: 11.88
+	Hs
		725139 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20
+	Hs
		724782 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23
+	Hs
		724893 MICA3_HUMAN (662-1403): 1.36e-13: 78.7: 12.99		MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23