HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: SYNE2 (Q8WXH0)
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Gene: SYNE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 6885
+	Hs
		1263707 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		SYNE2_HUMAN (1-6885): 0: 1508: 100.00
+	Hs
		1168761 C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28		SYNE3_HUMAN (4445-5053): 1.36e-10: 70.7: 13.84
+	Hs
		944680 MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27		PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20
+	Hs
		297837 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		K0754_HUMAN (317-2062): 4.78e-50: 201: 11.45
+	Hs
		965174 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MACF1_HUMAN (279-2502): 1.13e-48: 197: 10.79
+	Hs
		807779 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		SYNE1_HUMAN (5226-6861): 2.45e-16: 90.3: 9.43
+	Hs
		1068702 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		PLEC_HUMAN (4832-6877): 3.53e-41: 172: 10.20
+	Dm
		54271 Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84		A1Z9I8_DROME (385-2637): 1.37e-32: 144: 9.53
+	Hs
		521586 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		ACTN1_HUMAN (4678-5164): 1.7e-10: 70.6: 10.92
+	Hs
		993278 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		ACTN3_HUMAN (6427-6732): 2.66e-09: 66.3: 11.08
+	Dm
		115305 TITIN_DROME (148-1536): 1.72e-09: 65.1: 8.19		M9PEP8_DROME (1302-3225): 9.05e-23: 111: 10.87
+	Hs
		513849 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		DMD_HUMAN (5543-6849): 1.66e-16: 90.6: 10.27
+	Hs
		963451 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		SPTB2_HUMAN (5680-6855): 8.14e-12: 75.2: 10.24
+	Hs
		164604 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		SPTN2_HUMAN (2344-4109): 4.77e-15: 86: 7.96
+	Hs
		963292 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		SPTB2_HUMAN (5680-6855): 8.14e-12: 75.2: 10.24
+	Hs
		963358 MICA3_HUMAN (662-1403): 1.36e-13: 78.7: 12.99		SPTB2_HUMAN (5680-6855): 8.14e-12: 75.2: 10.24