HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 26638075, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 1193
+	Hs
		148913 CE170_HUMAN (1-1584): 0: 654: 100.00		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		1296672 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		1056879 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		MYH14_HUMAN (449-1088): 6.07e-13: 75.8: 14.74
+	Hs
		148818 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		724700 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		297837 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		K0754_HUMAN (4-1190): 2.58e-24: 113: 8.66
+	Hs
		944680 MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		1268090 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		551790 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		725013 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		1068702 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		1186077 MICA3_HUMAN (662-1403): 1.36e-13: 78.7: 12.99		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		149429 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		725139 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		148941 NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		724782 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		724893 MICA3_HUMAN (662-1403): 1.36e-13: 78.7: 12.99		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		149481 PCLO_HUMAN (88-1566): 4.63e-11: 70.2: 9.45		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Dm
		404245 TITIN_DROME (148-1536): 1.72e-09: 65.1: 8.19		MYSA_DROME (433-794): 1.65e-10: 68.1: 14.32