HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: KIF2C (Q99661)
Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK)
Gene: KIF2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26638075, 26496610
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005819 - spindle GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 725
+	Hs
		116847 CE170_HUMAN (1-1584): 0: 654: 100.00		KIF2A_HUMAN (10-722): 0: 626: 52.04
+	Hs
		1131769 CE170_HUMAN (1-1584): 0: 654: 100.00		KIF2B_HUMAN (10-698): 0: 554: 43.21
+	Hs
		1066231 CE170_HUMAN (1-1584): 0: 654: 100.00		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1131902 CE170_HUMAN (1-1584): 0: 654: 100.00		KIF3A_HUMAN (248-721): 2.78e-146: 445: 27.27
+	Hs
		1131836 CE170_HUMAN (1-1584): 0: 654: 100.00		KIFC3_HUMAN (15-623): 3.76e-138: 428: 23.34
+	Hs
		116937 C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28		KIF2A_HUMAN (10-722): 0: 626: 52.04
+	Hs
		1233721 C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28		KIF2B_HUMAN (10-698): 0: 554: 43.21
+	Hs
		116814 MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27		KIF2A_HUMAN (10-722): 0: 626: 52.04
+	Hs
		1056837 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		116903 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		KIF2A_HUMAN (10-722): 0: 626: 52.04
+	Hs
		1066677 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1066886 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1296683 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		KIFC3_HUMAN (15-623): 3.76e-138: 428: 23.34
+	Hs
		1066313 MICA3_HUMAN (662-1403): 1.36e-13: 78.7: 12.99		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Hs
		1066964 PCLO_HUMAN (88-1566): 4.63e-11: 70.2: 9.45		KIF14_HUMAN (40-685): 2.31e-143: 460: 23.38
+	Mm
		660029 ANK2_MOUSE (123-1379): 8.94e-11: 69.4: 13.83		KIF3A_MOUSE (248-721): 4.84e-146: 444: 26.67