HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: AKAP9 (Q99996)
A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)
Gene: AKAP9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26186194, 28514442, 35709258
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1584 Hs			1 3907
+	Hs
		1296675 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		AKAP9_HUMAN (1-3907): 0: 878: 100.00
+	Hs
		1131834 CE170_HUMAN (1-1584): 0: 654: 100.00		CP250_HUMAN (2-1330): 1.53e-46: 189: 10.71
+	Hs
		166721 CE170_HUMAN (1-1584): 0: 654: 100.00		CE290_HUMAN (2108-3900): 1.69e-42: 175: 10.38
+	Hs
		148913 CE170_HUMAN (1-1584): 0: 654: 100.00		CTRO_HUMAN (18-648): 1.78e-09: 66.5: 12.83
+	Hs
		148818 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		CTRO_HUMAN (18-648): 1.78e-09: 66.5: 12.83
+	Hs
		1296682 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		CP250_HUMAN (2-1330): 1.53e-46: 189: 10.71
+	Hs
		944680 MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27		PLEC_HUMAN (2053-3720): 9.98e-35: 150: 11.45
+	Hs
		724700 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		965174 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MACF1_HUMAN (883-3859): 6.57e-41: 170: 8.89
+	Hs
		1068702 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		PLEC_HUMAN (2053-3720): 9.98e-35: 150: 11.45
+	Hs
		1268090 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		MY18A_HUMAN (2166-2833): 7.07e-15: 84.3: 15.67
+	Hs
		725013 TARA_HUMAN (287-1532): 3.13e-27: 123: 8.21		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Dm
		1370292 Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84		Q9VTY8_DROME (1588-2292): 8.98e-18: 93.9: 15.68
+	Hs
		551790 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		DESP_HUMAN (2135-3311): 1.98e-09: 66.5: 13.94
+	Dm
		54892 Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84		A1ZA72_DROME (1714-3696): 9.58e-12: 74.4: 9.91
+	Hs
		724782 ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		149429 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		CTRO_HUMAN (18-648): 1.78e-09: 66.5: 12.83
+	Hs
		724893 MICA3_HUMAN (662-1403): 1.36e-13: 78.7: 12.99		MYH9_HUMAN (135-781): 3.02e-14: 82.3: 15.29
+	Hs
		317281 NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73		PCNT_HUMAN (220-863): 6.95e-11: 71.2: 11.28
+	Hs
		148941 NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73		CTRO_HUMAN (18-648): 1.78e-09: 66.5: 12.83