HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: KTNB1 (Q9BVA0)
Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)
Gene: KATNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26929214
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005819 - spindle GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 655
+	Hs
		1131796 CE170_HUMAN (1-1584): 0: 654: 100.00		FBXW7_HUMAN (48-344): 6.46e-76: 258: 22.52
+	Hs
		1281511 C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28		FBXW7_HUMAN (48-344): 6.46e-76: 258: 22.52
+	Hs
		209436 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		PLRG1_HUMAN (11-323): 1.18e-86: 282: 24.52
+	Hs
		929460 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		RACK1_HUMAN (92-302): 3.5e-46: 167: 25.23
+	Hs
		1056932 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		SNR40_HUMAN (181-384): 3.05e-30: 124: 17.62
+	Hs
		1281391 PRR36_HUMAN (98-1193): 6.71e-22: 105: 8.15		FBXW7_HUMAN (48-344): 6.46e-76: 258: 22.52
+	Hs
		807650 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		COPA_HUMAN (1-241): 6.51e-37: 150: 18.25
+	Hs
		152678 KMT2D_HUMAN (119-1312): 8.58e-09: 62.9: 5.85		FBXW7_HUMAN (48-344): 6.46e-76: 258: 22.52
+	Hs
		1346970 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		NLE1_HUMAN (180-470): 2.03e-43: 164: 15.39
+	Hs
		1302927 MINT_HUMAN (173-1570): 1.59e-17: 91.8: 7.72		NLE1_HUMAN (180-470): 2.03e-43: 164: 15.39
+	Hs
		1264784 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		SNR40_HUMAN (181-384): 3.05e-30: 124: 17.62
+	Hs
		1288394 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		SNR40_HUMAN (181-384): 3.05e-30: 124: 17.62
+	Hs
		1288258 MINT_HUMAN (173-1570): 1.59e-17: 91.8: 7.72		SNR40_HUMAN (181-384): 3.05e-30: 124: 17.62
+	Hs
		793042 SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74		LIS1_HUMAN (227-420): 5.51e-27: 115: 14.29
+	Hs
		903374 KMT2C_HUMAN (378-1460): 4.45e-12: 73.7: 11.24		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33
+	Hs
		152622 KMT2D_HUMAN (119-1312): 8.58e-09: 62.9: 5.85		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33
+	Hs
		152663 KMT2D_HUMAN (119-1312): 8.58e-09: 62.9: 5.85		WDR5B_HUMAN (261-467): 3.81e-12: 70.1: 7.66