HitPredict

Interactor 1: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Interactor 2: C170B (Q9Y4F5)
Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B)
Gene: CEP170B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26186194, 26638075, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FHA~FHA
Common GO terms	GO:0005874 - microtubule
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1584 Hs			1 1589
+	Hs
		1131724 CE170_HUMAN (1-1584): 0: 654: 100.00		CE170_HUMAN (1-1555): 2.86e-117: 408: 29.19
+	Hs
		1131811 CE170_HUMAN (1-1584): 0: 654: 100.00		C170L_HUMAN (1295-1555): 3.7e-45: 167: 35.06
+	Hs
		1131890 CE170_HUMAN (1-1584): 0: 654: 100.00		SRRM2_HUMAN (99-1578): 2.66e-17: 91: 10.59
+	Hs
		108768 H0Y2V6_HUMAN (100-1584): 8.62e-139: 469: 82.60		C170L_HUMAN (1295-1555): 3.7e-45: 167: 35.06
+	Hs
		1296700 C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28		C170L_HUMAN (1295-1555): 3.7e-45: 167: 35.06
+	Hs
		1056827 MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03		MDC1_HUMAN (111-750): 1.81e-19: 97.9: 8.75
+	Hs
		807690 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		ANK2_HUMAN (98-1539): 4.18e-46: 185: 9.87
+	Hs
		807793 MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56		PRG4_HUMAN (628-1586): 3.67e-31: 136: 8.66
+	Dm
		54595 Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84		A1Z9S6_DROME (98-1572): 7.55e-51: 201: 9.68
+	Hs
		1296671 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		C170L_HUMAN (1295-1555): 3.7e-45: 167: 35.06
+	Dm
		1366600 Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84		Q9VH10_DROME (111-1424): 2.07e-45: 183: 9.27
+	Hs
		1303336 MUC4_HUMAN (165-1560): 2.05e-33: 144: 9.47		MUC4_HUMAN (587-1585): 4.18e-21: 103: 9.55
+	Hs
		1263869 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		MUC16_HUMAN (129-1578): 1.8e-22: 108: 8.61
+	Hs
		554259 MUC1_HUMAN (1087-1574): 2.68e-22: 106: 10.61		MUC1_HUMAN (122-1134): 1.76e-27: 123: 11.70
+	Hs
		297837 C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23		K0754_HUMAN (815-1579): 5.77e-13: 76.5: 10.33
+	Hs
		1264771 TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68		TITIN_HUMAN (97-999): 5.28e-11: 70.2: 8.87
+	Dm
		1182373 Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84		Q7KU92_DROME (328-1292): 6.24e-11: 70.1: 12.46