HitPredict

Interactor 1: FREM2 (Q5SZK8)
FRAS1-related extracellular matrix protein 2 (ECM3 homolog)
Gene: FREM2

Interactor 2: PCDGD (Q9Y5G3)
Protocadherin gamma-B1 (PCDH-gamma-B1)
Gene: PCDHGB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 3169 Hs			1 927
+	Hs
		1167045 FAT4_HUMAN (208-1746): 0: 661: 11.21		PCDGD_HUMAN (1-912): 0: 1042: 100.00
+	Hs
		1295691 PCD16_HUMAN (1075-2621): 9.05e-160: 560: 10.70		PCDGD_HUMAN (1-912): 0: 1042: 100.00
+	Hs
		1295693 PCD16_HUMAN (1075-2621): 9.05e-160: 560: 10.70		PCDG6_HUMAN (1-912): 0: 981: 52.01
+	Hs
		1295692 PCD16_HUMAN (1075-2621): 9.05e-160: 560: 10.70		PCDG7_HUMAN (1-912): 0: 972: 51.47
+	Hs
		1348649 CELR1_HUMAN (32-1073): 6.24e-102: 371: 11.24		PCDGD_HUMAN (1-912): 0: 1042: 100.00
+	Hs
		1336517 CELR2_HUMAN (31-1075): 7.48e-97: 354: 12.65		PCDGD_HUMAN (1-912): 0: 1042: 100.00
+	Hs
		1344895 PCDBG_HUMAN (54-728): 1.04e-51: 200: 10.73		PCDGD_HUMAN (1-912): 0: 1042: 100.00
+	Hs
		1348659 CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33		PCDGD_HUMAN (1-912): 0: 1042: 100.00
+	Hs
		1377975 PCDBD_HUMAN (54-695): 3.04e-52: 202: 10.38		PCDB3_HUMAN (1-764): 0: 591: 44.72
+	Hs
		1344894 PCDBG_HUMAN (54-728): 1.04e-51: 200: 10.73		PCDB3_HUMAN (1-764): 0: 591: 44.72
+	Hs
		1344892 PCDBG_HUMAN (54-728): 1.04e-51: 200: 10.73		PCDB7_HUMAN (1-772): 0: 588: 44.98
+	Hs
		1357384 PCDB8_HUMAN (54-695): 1.51e-50: 197: 10.96		PCDB3_HUMAN (1-764): 0: 591: 44.72
+	Hs
		1344890 PCDBG_HUMAN (54-728): 1.04e-51: 200: 10.73		PCDBA_HUMAN (11-764): 0: 577: 45.12
+	Hs
		1348658 CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33		PCDGH_HUMAN (1-440): 1.8e-103: 345: 23.14
+	Hs
		1348654 CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33		PCDGG_HUMAN (1-440): 4.25e-98: 330: 23.80
+	Hs
		1377989 PCDBD_HUMAN (54-695): 3.04e-52: 202: 10.38		PCDBB_HUMAN (347-927): 2.69e-84: 289: 17.31
+	Hs
		1348657 CELR3_HUMAN (55-554): 1.01e-44: 182: 11.33		PCDBB_HUMAN (347-927): 2.69e-84: 289: 17.31
+	Hs
		1357389 PCDB6_HUMAN (26-555): 7.51e-29: 128: 13.06		PCDGK_HUMAN (1-439): 5.57e-96: 324: 25.00
+	Hs
		1344893 PCDBG_HUMAN (54-728): 1.04e-51: 200: 10.73		PCDB6_HUMAN (557-925): 4.43e-22: 104: 10.35