HitPredict

Interactor 1: C2D1B (Q5T0F9)
Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2)
Gene: CC2D1B

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 31586073, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 224
+	Hs
		1158648 C2D1A_HUMAN (6-855): 1.16e-100: 336: 42.47		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		1158636 C2D1A_HUMAN (6-855): 1.16e-100: 336: 42.47		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Dm
		1249816 C2D1_DROME (8-854): 3.75e-103: 339: 30.77		CHM4_DROME (1-222): 3.22e-45: 151: 56.28
+	Hs
		1158643 C2D1A_HUMAN (6-855): 1.16e-100: 336: 42.47		CHM4A_HUMAN (1-220): 2.41e-43: 147: 56.95
+	Hs
		1217637 NAV2_HUMAN (103-527): 5.76e-27: 120: 14.82		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1056930 MDC1_HUMAN (5-610): 3.28e-14: 79.4: 8.40		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1264782 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78