HitPredict

Interactor 1: MPP7 (Q5T2T1)
MAGUK p55 subfamily member 7
Gene: MPP7

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.665

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0060090 - molecular adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 576 Hs			1 992
+	Hs
		159290 CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		1232514 PALS1_HUMAN (28-574): 1.04e-123: 380: 37.70		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		1132899 MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Mm
		251107 CSKP_MOUSE (1-575): 1.07e-130: 406: 30.17		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Hs
		4618 MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		159281 CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4613 CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		1021594 DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Rn
		957008 DLG1_RAT (2-227): 4.63e-25: 112: 15.35		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Hs
		145947 DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145949 DLG2_HUMAN (62-221): 2.34e-23: 107: 15.66		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Rn
		956989 DLG1_RAT (2-227): 4.63e-25: 112: 15.35		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Mm
		1195008 DLG1_MOUSE (2-228): 1.15e-24: 110: 14.46		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		957000 DLG1_RAT (2-227): 4.63e-25: 112: 15.35		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Hs
		1021580 DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4617 DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		1077291 DLG2_HUMAN (62-221): 2.34e-23: 107: 15.66		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		327239 DLG2_HUMAN (62-221): 2.34e-23: 107: 15.66		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Rn
		957005 DLG1_RAT (2-227): 4.63e-25: 112: 15.35		DLGP3_RAT (1-992): 0: 962: 35.20
+	Hs
		1077280 DLG2_HUMAN (62-221): 2.34e-23: 107: 15.66		Q6IS01_HUMAN (1-551): 0: 679: 43.37