HitPredict

Interactor 1: HECD3 (Q5T447)
E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3)
Gene: HECTD3

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 861 Hs			1 783
+	Hs
		1171253 ITCH_HUMAN (318-855): 0: 545: 17.83		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		808169 NEDD4_HUMAN (322-853): 5.8e-176: 545: 18.46		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171774 SMUF2_HUMAN (336-855): 3.41e-177: 531: 20.32		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171305 NED4L_HUMAN (374-853): 1.61e-171: 524: 19.11		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171800 SMUF1_HUMAN (336-855): 2.1e-167: 506: 17.88		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170603 HUWE1_HUMAN (329-854): 6.82e-152: 496: 19.78		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1078017 HERC1_HUMAN (517-855): 3.98e-53: 204: 36.72		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		319890 HERC2_HUMAN (237-372): 5.72e-44: 175: 35.77		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Mm
		1186495 HUWE1_MOUSE (329-854): 1.01e-151: 496: 19.78		TRIM3_MOUSE (190-767): 6.68e-78: 268: 14.85
+	Mm
		1118130 HERC2_MOUSE (237-372): 1.43e-43: 174: 35.77		TRI67_MOUSE (1-783): 0: 574: 89.40
+	Hs
		262198 HECW2_HUMAN (336-855): 4.75e-146: 471: 20.34		TRIM3_HUMAN (190-767): 1.26e-78: 270: 15.01
+	Hs
		1072690 UBE3C_HUMAN (495-845): 2.66e-20: 99: 27.64		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1061473 CUL7_HUMAN (245-370): 1.55e-18: 93.6: 40.63		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		195713 ZZEF1_HUMAN (233-369): 8.7e-18: 91.3: 34.06		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		125454 WWP2_HUMAN (321-855): 1.45e-172: 523: 17.74		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		1290890 SMUF1_HUMAN (336-855): 2.1e-167: 506: 17.88		TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66
+	Hs
		1052695 HUWE1_HUMAN (329-854): 6.82e-152: 496: 19.78		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		1052789 HECW2_HUMAN (336-855): 4.75e-146: 471: 20.34		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29
+	Hs
		1052657 CUL7_HUMAN (245-370): 1.55e-18: 93.6: 40.63		TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29