HitPredict

Interactor 1: TMTC4 (Q5T4D3)
Protein O-mannosyl-transferase TMTC4 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 4) (Transmembrane and tetratricopeptide repeat-containing 4)
Gene: TMTC4

Interactor 2: TXD15 (Q96J42)
Thioredoxin domain-containing protein 15
Gene: TXNDC15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 741 Hs			1 360
+	Hs
		531878 TMTC3_HUMAN (397-733): 1.72e-44: 174: 17.14		PDIA4_HUMAN (104-305): 2.62e-35: 137: 20.48
+	Hs
		174647 OGT1_HUMAN (305-596): 4.06e-22: 104: 15.46		PDIA3_HUMAN (133-304): 1.24e-35: 137: 16.20
+	Hs
		174905 OGT1_HUMAN (305-596): 4.06e-22: 104: 15.46		PDIA6_HUMAN (181-324): 6.16e-35: 134: 19.61
+	Hs
		174553 OGT1_HUMAN (305-596): 4.06e-22: 104: 15.46		PDIA1_HUMAN (141-293): 1.49e-30: 123: 17.61
+	Hs
		531908 TTC13_HUMAN (423-615): 1.68e-16: 85.9: 13.99		PDIA4_HUMAN (104-305): 2.62e-35: 137: 20.48
+	Hs
		175045 OGT1_HUMAN (305-596): 4.06e-22: 104: 15.46		TXND5_HUMAN (212-331): 2.39e-28: 116: 20.80
+	Hs
		174887 OGT1_HUMAN (305-596): 4.06e-22: 104: 15.46		PDIA5_HUMAN (55-292): 2.8e-23: 102: 16.94
+	Hs
		684738 STIP1_HUMAN (655-739): 5.43e-09: 61.2: 14.12		PDIA6_HUMAN (181-324): 6.16e-35: 134: 19.61
+	Hs
		423334 BBS4_HUMAN (611-740): 3.16e-09: 62: 18.80		PDIA1_HUMAN (141-293): 1.49e-30: 123: 17.61
+	Hs
		423156 STIP1_HUMAN (655-739): 5.43e-09: 61.2: 14.12		PDIA1_HUMAN (141-293): 1.49e-30: 123: 17.61
+	Hs
		684887 STIP1_HUMAN (655-739): 5.43e-09: 61.2: 14.12		TXND5_HUMAN (212-331): 2.39e-28: 116: 20.80