Interactor 1: SFRP5 (Q5T4F7)
Secreted frizzled-related protein 5 (sFRP-5) (Frizzled-related protein 1b) (FRP-1b) (Secreted apoptosis-related protein 3) (SARP-3)
Gene: SFRP5

Interactor 2: SFRP2 (Q96HF1)
Secreted frizzled-related protein 2 (FRP-2) (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1)
Gene: SFRP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 17123353
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Fz~Fz
Common GO terms GO:0005615 - extracellular space
GO:0008285 - negative regulation of cell population proliferation
GO:0017147 - Wnt-protein binding
GO:0030178 - negative regulation of Wnt signaling pathway
GO:0035567 - non-canonical Wnt signaling pathway
and 3 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 317
Hs

1 295
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Hs
+ Rn
+ Dm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024