HitPredict

Interactor 1: WLS (Q5T9L3)
Protein wntless homolog (Integral membrane protein GPR177) (Protein evenness interrupted homolog) (EVI) (Putative NF-kappa-B-activating protein 373)
Gene: WLS

Interactor 2: WNT8B (Q93098)
Protein Wnt-8b
Gene: WNT8B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	22784633
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MIG-14_Wnt-bd~wnt
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 351
+	Hs
		1135437 WLS_HUMAN (1-541): 0: 811: 100.00		WNT8A_HUMAN (1-336): 7.95e-156: 442: 64.60
+	Hs
		135861 WLS_HUMAN (1-541): 0: 811: 100.00		WNT7A_HUMAN (1-334): 3.18e-146: 418: 39.71
+	Mm
		568285 WLS_MOUSE (1-541): 0: 812: 96.12		WNT3_MOUSE (25-334): 3.75e-142: 408: 39.19
+	Hs
		881899 WLS_HUMAN (1-541): 0: 811: 100.00		WNT7B_HUMAN (1-334): 1.47e-142: 408: 40.29
+	Mm
		611175 WLS_MOUSE (1-541): 0: 812: 96.12		WNT5A_MOUSE (36-334): 6.14e-139: 401: 39.74
+	Hs
		782089 WLS_HUMAN (1-541): 0: 811: 100.00		WNT5A_HUMAN (36-334): 4.77e-139: 401: 39.74
+	Hs
		1135438 WLS_HUMAN (1-541): 0: 811: 100.00		WNT5B_HUMAN (17-334): 7.02e-138: 397: 37.05
+	Hs
		881860 WLS_HUMAN (1-541): 0: 811: 100.00		WNT3A_HUMAN (20-334): 7.1e-137: 394: 38.58
+	Hs
		881881 WLS_HUMAN (1-541): 0: 811: 100.00		WNT4_HUMAN (8-334): 5.02e-133: 385: 40.48
+	Mm
		382254 WLS_MOUSE (1-541): 0: 812: 96.12		WNT1_MOUSE (42-333): 1.24e-127: 371: 41.41
+	Hs
		451998 WLS_HUMAN (1-541): 0: 811: 100.00		WNT2_HUMAN (20-337): 6.46e-128: 372: 38.72
+	Hs
		384072 WLS_HUMAN (1-541): 0: 811: 100.00		WNT1_HUMAN (42-333): 1.43e-127: 371: 41.41
+	Hs
		1135451 WLS_HUMAN (1-541): 0: 811: 100.00		WNT16_HUMAN (34-334): 4.48e-122: 357: 37.14
+	Hs
		158076 WLS_HUMAN (1-541): 0: 811: 100.00		WNT9B_HUMAN (40-334): 7.87e-108: 321: 37.62
+	Hs
		158068 WLS_HUMAN (1-541): 0: 811: 100.00		WNT9A_HUMAN (40-334): 3.97e-102: 306: 36.60
+	Dm
		658764 WLS_DROME (1-535): 0: 642: 40.82		WNT2_DROME (3-334): 2.67e-109: 324: 34.09
+	Dm
		776060 WLS_DROME (1-535): 0: 642: 40.82		WNT4_DROME (42-334): 8.97e-95: 293: 28.67
+	Dm
		1279554 WLS_DROME (1-535): 0: 642: 40.82		Q9VM25_DROME (40-317): 1.01e-82: 261: 27.06
+	Dm
		658776 WLS_DROME (1-535): 0: 642: 40.82		WNT5_DROME (38-155): 1.29e-43: 162: 29.66
+	Dm
		452324 WLS_DROME (1-535): 0: 642: 40.82		WNTG_DROME (232-333): 2.6e-34: 133: 32.35