Interactor 1: INT11 (Q5TA45)
Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)
Gene: INTS11

Interactor 2: INT4 (Q96HW7)
Integrator complex subunit 4 (Int4)
Gene: INTS4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 28396433, 33548203
Identification Methods anti tag coimmunoprecipitation, pull down, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Beta-Casp~HEAT_2, HEAT_2~Lactamase_B_6
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016180 - snRNA processing
GO:0032039 - integrator complex
GO:0034243 - regulation of transcription elongation by RNA polymerase II
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 600
Hs

1 963
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024