HitPredict

Interactor 1: LCE2D (Q5TA82)
Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A)
Gene: LCE2D

Interactor 2: KRA54 (Q6L8H1)
Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4)
Gene: KRTAP5-4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Hs			1 288
+	Hs
		888713 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR101_HUMAN (8-254): 6.39e-22: 94.5: 16.23
+	Hs
		888712 LCE2C_HUMAN (1-110): 2.19e-47: 148: 96.36		KR101_HUMAN (8-254): 6.39e-22: 94.5: 16.23
+	Hs
		889070 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR105_HUMAN (1-254): 1.11e-20: 91: 16.54
+	Hs
		889069 LCE2C_HUMAN (1-110): 2.19e-47: 148: 96.36		KR105_HUMAN (1-254): 1.11e-20: 91: 16.54
+	Hs
		889791 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR109_HUMAN (132-286): 1.64e-13: 71: 23.23
+	Hs
		1135749 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR411_HUMAN (4-197): 6.38e-14: 70.5: 21.03
+	Hs
		889280 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR107_HUMAN (110-285): 2.95e-12: 67.9: 23.50
+	Hs
		889165 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR106_HUMAN (1-265): 6.35e-12: 67.1: 19.56
+	Hs
		889279 LCE2C_HUMAN (1-110): 2.19e-47: 148: 96.36		KR107_HUMAN (110-285): 2.95e-12: 67.9: 23.50
+	Hs
		889164 LCE2C_HUMAN (1-110): 2.19e-47: 148: 96.36		KR106_HUMAN (1-265): 6.35e-12: 67.1: 19.56
+	Hs
		889521 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR108_HUMAN (3-168): 1.23e-11: 65.2: 17.94
+	Hs
		889520 LCE2C_HUMAN (1-110): 2.19e-47: 148: 96.36		KR108_HUMAN (3-168): 1.23e-11: 65.2: 17.94
+	Hs
		1135748 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KRA92_HUMAN (110-279): 6.72e-11: 61.6: 22.03
+	Hs
		1135743 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KR412_HUMAN (5-207): 1.93e-10: 60.9: 18.63
+	Hs
		1135746 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KRA98_HUMAN (139-284): 2.52e-10: 59.7: 22.15
+	Hs
		887738 LCE2C_HUMAN (1-110): 2.19e-47: 148: 96.36		KR10A_HUMAN (120-285): 1.85e-09: 58.9: 26.67
+	Hs
		1135747 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KRA93_HUMAN (206-285): 1.34e-09: 57.8: 40.00
+	Hs
		1135753 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KRA42_HUMAN (129-259): 1.61e-09: 57: 30.30
+	Hs
		1135750 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KRA41_HUMAN (189-285): 3.07e-09: 56.6: 40.74
+	Hs
		1135752 LCE2D_HUMAN (1-110): 1.23e-47: 149: 100.00		KRA44_HUMAN (162-284): 3.84e-09: 56.6: 39.52