HitPredict

Interactor 1: DCAF8 (Q5TAQ9)
DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)
Gene: DCAF8

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	37689310, 21145461
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 597 Hs			1 334
+	Hs
		1272536 DCAF5_HUMAN (153-542): 6e-79: 269: 22.72		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Mm
		193523 WDTC1_MOUSE (405-597): 3.07e-46: 175: 29.80		CSN5_MOUSE (1-334): 1.02e-130: 378: 99.40
+	Hs
		1234360 WDTC1_HUMAN (405-597): 4.23e-46: 174: 30.30		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		903414 WDR5_HUMAN (278-585): 2.83e-45: 165: 12.18		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		130829 WDR5_HUMAN (278-585): 2.83e-45: 165: 12.18		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		124920 FBXW7_HUMAN (312-594): 7.67e-52: 191: 12.28		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Mm
		643126 WDTC1_MOUSE (405-597): 3.07e-46: 175: 29.80		PSMD7_MOUSE (52-325): 7.97e-67: 214: 14.79
+	Hs
		124819 WDR5_HUMAN (278-585): 2.83e-45: 165: 12.18		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		1138819 SNR40_HUMAN (83-358): 2.66e-47: 171: 14.69		MYSM1_HUMAN (39-172): 3.5e-29: 119: 23.29