HitPredict

Interactor 1: DCAF8 (Q5TAQ9)
DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)
Gene: DCAF8

Interactor 2: ARHGQ (Q96DR7)
Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)
Gene: ARHGEF26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 597 Hs			1 871
+	Hs
		1135860 DCAF8_HUMAN (1-597): 5.38e-132: 400: 100.00		FARP1_HUMAN (217-863): 5.87e-79: 278: 15.16
+	Mm
		1194779 WDTC1_MOUSE (405-597): 3.07e-46: 175: 29.80		NGEF_MOUSE (197-868): 2.18e-114: 367: 27.88
+	Hs
		164142 FBXW7_HUMAN (312-594): 7.67e-52: 191: 12.28		ARHGA_HUMAN (69-758): 2.51e-95: 328: 18.40
+	Hs
		1288311 SNR40_HUMAN (83-358): 2.66e-47: 171: 14.69		ECT2_HUMAN (262-825): 3.77e-78: 274: 16.29
+	Hs
		903526 WDR5_HUMAN (278-585): 2.83e-45: 165: 12.18		ECT2_HUMAN (262-825): 3.77e-78: 274: 16.29
+	Hs
		1254029 NLE1_HUMAN (86-182): 4.74e-11: 67.2: 8.25		PREX1_HUMAN (391-824): 9.37e-82: 290: 18.50
+	Hs
		1016327 TBL3_HUMAN (76-182): 1.35e-09: 63: 9.35		ECT2_HUMAN (262-825): 3.77e-78: 274: 16.29
+	Hs
		1288351 SNR40_HUMAN (83-358): 2.66e-47: 171: 14.69		ITSN2_HUMAN (432-693): 4.27e-22: 105: 27.57
+	Hs
		61736 SNR40_HUMAN (83-358): 2.66e-47: 171: 14.69		A6H8W8_HUMAN (432-693): 4.96e-22: 104: 27.57
+	Hs
		1016339 TBL3_HUMAN (76-182): 1.35e-09: 63: 9.35		ITSN2_HUMAN (432-693): 4.27e-22: 105: 27.57