HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: LARP1 (Q6PKG0)
La-related protein 1 (La ribonucleoprotein domain family member 1)
Gene: LARP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26170170, 30209976, 23663784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0010494 - cytoplasmic stress granule GO:0010608 - post-transcriptional regulation of gene expression
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 1096
+	Hs
		1136121 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		LAR1B_HUMAN (175-1093): 0: 632: 55.38
+	Hs
		1162685 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		LARP1_HUMAN (1-1096): 0: 747: 100.00
+	Hs
		1136139 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		1136206 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23
+	Hs
		1174856 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		LARP4_HUMAN (309-860): 6.21e-41: 164: 13.73
+	Hs
		1268172 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		LAR4B_HUMAN (274-867): 1.43e-32: 138: 13.23