HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: YTHD3 (Q7Z739)
YTH domain-containing family protein 3 (DF3)
Gene: YTHDF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0010494 - cytoplasmic stress granule GO:0043488 - regulation of mRNA stability
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 585
+	Hs
		1136382 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD2_HUMAN (1-581): 6.75e-156: 460: 65.81
+	Hs
		1136271 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD1_HUMAN (1-570): 2.77e-137: 412: 66.55
+	Hs
		1136291 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC2_HUMAN (286-551): 2.37e-57: 210: 21.61
+	Hs
		1136237 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC1_HUMAN (327-581): 1.19e-53: 196: 18.38
+	Hs
		1192380 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD3_HUMAN (1-568): 2.64e-171: 500: 100.00
+	Hs
		1335263 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD2_HUMAN (1-581): 6.75e-156: 460: 65.81
+	Hs
		1317023 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD1_HUMAN (1-570): 2.77e-137: 412: 66.55
+	Hs
		1332440 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC2_HUMAN (286-551): 2.37e-57: 210: 21.61
+	Hs
		1298137 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC1_HUMAN (327-581): 1.19e-53: 196: 18.38