HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: YTDC1 (Q96MU7)
YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)
Gene: YTHDC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0010608 - post-transcriptional regulation of gene expression
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 727
+	Hs
		1136382 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD2_HUMAN (300-520): 2.5e-88: 290: 23.71
+	Hs
		1136147 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD3_HUMAN (300-503): 4.24e-83: 276: 22.48
+	Hs
		1136271 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTHD1_HUMAN (300-521): 7.77e-81: 270: 22.55
+	Hs
		1136291 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		YTDC2_HUMAN (253-493): 1.34e-53: 202: 35.22
+	Hs
		1298137 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC1_HUMAN (1-673): 0: 567: 100.00
+	Hs
		1335263 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD2_HUMAN (300-520): 2.5e-88: 290: 23.71
+	Hs
		1192380 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD3_HUMAN (300-503): 4.24e-83: 276: 22.48
+	Hs
		1317023 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTHD1_HUMAN (300-521): 7.77e-81: 270: 22.55
+	Hs
		1332440 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		YTDC2_HUMAN (253-493): 1.34e-53: 202: 35.22