HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 23663784
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0003729 - mRNA binding GO:0035198 - miRNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 783
+	Hs
		1136251 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1136209 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134078 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		1335187 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		DDX21_HUMAN (1-783): 0: 543: 100.00
+	Hs
		1308875 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		DDX50_HUMAN (49-728): 1.52e-137: 425: 59.12
+	Hs
		1271665 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134212 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		757769 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23