HitPredict

Interactor 1: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29395067, 30209976, 23663784
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0010494 - cytoplasmic stress granule
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1133 Hs			1 599
+	Hs
		128201 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1136332 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1072106 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		1136232 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		903980 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		HNRPK_HUMAN (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		1071900 RC3H1_HUMAN (1-1133): 0: 1909: 100.00		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69
+	Hs
		1335270 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		128307 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1335208 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1072185 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		PCBP2_HUMAN (422-597): 7.25e-36: 140: 26.92
+	Hs
		1294257 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		1072026 RC3H2_HUMAN (1-1107): 0: 1494: 51.72		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69