HitPredict

Interactor 1: MAGI3 (Q5TCQ9)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)
Gene: MAGI3

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1481 Hs			1 992
+	Hs
		145951 MAGI2_HUMAN (1-1356): 2.23e-159: 522: 40.55		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		1199792 MAGI2_HUMAN (1-1356): 2.23e-159: 522: 40.55		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		327243 MAGI2_HUMAN (1-1356): 2.23e-159: 522: 40.55		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		1021594 DLG1_HUMAN (14-594): 2.26e-26: 119: 9.03		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Rn
		291499 MAGI2_RAT (308-1386): 4.83e-35: 148: 12.55		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Mm
		1257407 MPDZ_MOUSE (518-934): 1.37e-42: 173: 20.05		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		291496 MAGI2_RAT (308-1386): 4.83e-35: 148: 12.55		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Hs
		145947 DLG1_HUMAN (14-594): 2.26e-26: 119: 9.03		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		145952 DLG3_HUMAN (16-398): 1.65e-24: 113: 8.95		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Rn
		956992 DLG2_RAT (2-207): 4.15e-26: 118: 14.22		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Rn
		956987 GRIP1_RAT (680-1469): 3.29e-25: 116: 11.35		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Rn
		956995 NHRF3_RAT (15-542): 5.69e-25: 113: 12.03		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Mm
		1265187 DLG2_MOUSE (2-207): 6.64e-26: 117: 14.22		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Mm
		1195008 DLG1_MOUSE (14-341): 2.85e-25: 115: 9.67		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		291497 MAGI2_RAT (308-1386): 4.83e-35: 148: 12.55		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Hs
		1153633 MAGI2_HUMAN (1-1356): 2.23e-159: 522: 40.55		Q6IS01_HUMAN (1-551): 0: 679: 43.37
+	Hs
		1021580 DLG1_HUMAN (14-594): 2.26e-26: 119: 9.03		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4617 DLG1_HUMAN (14-594): 2.26e-26: 119: 9.03		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4619 DLG3_HUMAN (16-398): 1.65e-24: 113: 8.95		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Rn
		291498 MAGI2_RAT (308-1386): 4.83e-35: 148: 12.55		DLGP3_RAT (1-992): 0: 962: 35.20