Interactor 1: M3K21 (Q5TCX8)
Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4)
Gene: MAP3K21

Interactor 2: TESK2 (Q96S53)
Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2)
Gene: TESK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27173435
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1036
Hs

1 571
+ At
+ Mm
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+ Hs
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Last updated: 15 Jul 2024