HitPredict

Interactor 1: M3K21 (Q5TCX8)
Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4)
Gene: MAP3K21

Interactor 2: LRFN1 (Q9P244)
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2)
Gene: LRFN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~fn3, LRR_8~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1036 Hs			1 771
+	At
		83843 BRL3_ARATH (4-430): 3.81e-123: 406: 19.20		Y5614_ARATH (1-582): 1.13e-60: 223: 13.58
+	At
		83837 SERK1_ARATH (1-443): 8.68e-128: 403: 18.97		Y5614_ARATH (1-582): 1.13e-60: 223: 13.58
+	At
		1258432 SIS8_ARATH (66-422): 1.93e-102: 347: 30.89		MIK2_ARATH (2-633): 9.44e-63: 229: 11.16
+	At
		84489 BRL3_ARATH (4-430): 3.81e-123: 406: 19.20		GSO1_ARATH (1-256): 8.81e-43: 170: 18.57
+	At
		84511 BRL1_ARATH (4-430): 6.46e-123: 405: 20.31		GSO1_ARATH (1-256): 8.81e-43: 170: 18.57
+	At
		84479 BAK1_ARATH (1-450): 1.24e-126: 400: 19.03		GSO1_ARATH (1-256): 8.81e-43: 170: 18.57
+	At
		84454 Y5457_ARATH (3-429): 8.04e-124: 393: 18.12		GSO1_ARATH (1-256): 8.81e-43: 170: 18.57
+	At
		1338257 BRL3_ARATH (4-430): 3.81e-123: 406: 19.20		BAME2_ARATH (1-132): 2.41e-19: 95.5: 16.42
+	At
		287480 SERK2_ARATH (1-443): 2.69e-127: 402: 18.97		SKM1_ARATH (135-470): 4.7e-17: 88.2: 11.95
+	At
		85050 Y5457_ARATH (3-429): 8.04e-124: 393: 18.12		BAME2_ARATH (1-132): 2.41e-19: 95.5: 16.42
+	At
		287464 BAK1_ARATH (1-450): 1.24e-126: 400: 19.03		SKM1_ARATH (135-470): 4.7e-17: 88.2: 11.95
+	At
		85004 Y5457_ARATH (3-429): 8.04e-124: 393: 18.12		SKM1_ARATH (135-470): 4.7e-17: 88.2: 11.95
+	At
		1376822 SERK2_ARATH (1-443): 2.69e-127: 402: 18.97		BRL2_ARATH (122-517): 7.33e-10: 64.7: 11.94
+	At
		85062 Y5457_ARATH (3-429): 8.04e-124: 393: 18.12		BRL2_ARATH (122-517): 7.33e-10: 64.7: 11.94