HitPredict

Interactor 1: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Interactor 2: PSMD1 (Q99460)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 399 Hs			1 953
+	Hs
		1259550 DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		1303954 UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		1303948 UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		1303937 UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Hs
		872202 RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00		PSMD1_HUMAN (1-953): 0: 1310: 100.00
+	Dm
		1359018 Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39		PSMD1_DROME (2-933): 0: 1114: 61.64
+	Hs
		1027692 DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		1027733 DDI1_HUMAN (1-392): 7.44e-148: 426: 70.75		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Sc
		693266 RAD23_YEAST (5-202): 3.88e-26: 110: 16.00		RPN2_YEAST (2-953): 0: 984: 40.26
+	Hs
		1027821 UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		1027815 UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		1027806 UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		872151 RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Hs
		923974 RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06		PSMD2_HUMAN (8-796): 0: 802: 18.73
+	Dm
		1374998 Q9VWD9_DROME (5-241): 8.99e-44: 161: 16.39		Q9VW54_DROME (12-796): 0: 702: 16.86
+	Dm
		1362832 Q9VCD5_DROME (5-227): 2.18e-35: 133: 12.88		Q9VW54_DROME (12-796): 0: 702: 16.86
+	Sp
		953205 DSK2_SCHPO (10-179): 8.15e-29: 117: 17.87		RPN1_SCHPO (8-794): 0: 666: 18.03
+	Sc
		753827 DDI1_YEAST (3-395): 7.99e-93: 287: 30.92		RPN1_YEAST (8-604): 4.59e-149: 468: 15.96
+	Sc
		753873 DSK2_YEAST (19-213): 6.83e-31: 123: 15.49		RPN1_YEAST (8-604): 4.59e-149: 468: 15.96
+	Sc
		697080 RAD23_YEAST (5-202): 3.88e-26: 110: 16.00		RPN1_YEAST (8-604): 4.59e-149: 468: 15.96