HitPredict

Interactor 1: BIG3 (Q5TH69)
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)
Gene: ARFGEF3

Interactor 2: CLC2D (Q9UHP7)
C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin)
Gene: CLEC2D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2177 Hs			1 191
+	Hs
		1355547 BIG1_HUMAN (542-1861): 0: 883: 15.57		CLC2D_HUMAN (1-191): 2.05e-63: 196: 100.00
+	Hs
		1355546 BIG2_HUMAN (610-1861): 0: 866: 16.05		CLC2D_HUMAN (1-191): 2.05e-63: 196: 100.00
+	Hs
		1357317 BIG2_HUMAN (610-1861): 0: 866: 16.05		CLC4A_HUMAN (42-191): 3.17e-38: 133: 18.79
+	Hs
		1265980 BIG2_HUMAN (610-1861): 0: 866: 16.05		CLC2B_HUMAN (48-187): 3.95e-37: 127: 41.43
+	Hs
		1265921 GBF1_HUMAN (610-1749): 4.62e-125: 440: 11.69		CLC2B_HUMAN (48-187): 3.95e-37: 127: 41.43