HitPredict

Interactor 1: UBP2 (Q5U349)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Ubiquitin-specific-processing protease testis) (UBP-t)
Gene: Usp2

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10938131
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Rn			1 810
+	Hs
		271022 UBP2_HUMAN (1-618): 0: 618: 89.00		UBC_HUMAN (1-533): 0: 662: 99.81
+	Dm
		477538 NOT_DROME (267-612): 1.08e-109: 340: 32.58		UBIQP_DROME (77-801): 0: 887: 97.38
+	Hs
		475440 UBP8_HUMAN (33-615): 9.13e-135: 423: 28.15		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476545 UBP21_HUMAN (99-617): 1.78e-119: 368: 34.63		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476579 UBP22_HUMAN (245-612): 4.2e-115: 355: 29.63		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		64200 UBP27_HUMAN (212-612): 1.51e-112: 345: 27.63		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476493 UBP36_HUMAN (161-611): 9.46e-102: 335: 25.93		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475566 UBP46_HUMAN (256-613): 4.61e-109: 334: 25.40		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476658 UBP3_HUMAN (233-615): 7.06e-107: 334: 31.95		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		259261 UBP12_HUMAN (256-613): 1.56e-108: 332: 25.40		UBC_HUMAN (1-533): 0: 662: 99.81
+	At
		1210479 UBP15_ARATH (11-617): 1.16e-121: 384: 20.67		UBQ10_ARATH (381-801): 9.04e-177: 517: 91.69
+	Sc
		477294 UBP5_YEAST (128-611): 1.25e-105: 339: 26.38		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	Hs
		271114 UBP2_HUMAN (1-618): 0: 618: 89.00		Q5U5U6_HUMAN (1-77): 1.17e-26: 110: 98.70
+	At
		1092065 UBP15_ARATH (11-617): 1.16e-121: 384: 20.67		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Mm
		476865 UBP8_MOUSE (32-615): 6.09e-138: 430: 27.94		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		924201 UBP36_HUMAN (161-611): 9.46e-102: 335: 25.93		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		398134 UBP21_HUMAN (99-617): 1.78e-119: 368: 34.63		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Mm
		477008 UBP12_MOUSE (256-613): 7.9e-110: 336: 25.94		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		476741 UBP46_MOUSE (256-613): 4.61e-109: 334: 25.40		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		474982 UBP46_HUMAN (256-613): 4.61e-109: 334: 25.40		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70