HitPredict

Interactor 1: Q5U5U6 (Q5U5U6)
Epididymis secretory protein Li 50 (Ubiquitin B)
Gene: UBB

Interactor 2: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 207
+	Hs
		475124 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00
+	Hs
		475249 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01
+	Hs
		474984 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Dm
		639414 Q9W418_DROME (1-228): 2.1e-92: 282: 100.00		UBCD1_DROME (61-206): 9.93e-82: 241: 64.38
+	Sc
		477103 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		UBC4_YEAST (60-206): 2.11e-80: 237: 63.95
+	Hs
		474958 UBB_HUMAN (1-229): 4.07e-98: 286: 100.00		UBE2A_HUMAN (59-204): 1.17e-69: 210: 35.62
+	Dr
		94560 F1QHN6_DANRE (1-228): 3.12e-92: 282: 100.00		Q7T3F3_DANRE (59-206): 2.34e-70: 212: 44.60
+	Hs
		476155 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00
+	Rn
		88580 UBC_RAT (1-181): 2.6e-61: 206: 96.13		UB2D1_RAT (61-206): 9.93e-82: 241: 61.64
+	Mm
		476737 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		UB2D3_MOUSE (61-206): 1.1e-80: 238: 64.38
+	Hs
		475586 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		475501 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		475550 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Rn
		1144263 UBC_RAT (1-181): 2.6e-61: 206: 96.13		UBE2N_RAT (59-206): 1.53e-70: 213: 44.60
+	Hs
		475504 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Mm
		476739 UBC_MOUSE (1-181): 6.49e-62: 207: 96.13		UBE2N_MOUSE (59-206): 3.58e-69: 209: 45.27
+	Sc
		477372 UBI4P_YEAST (1-228): 5.66e-90: 271: 96.05		UBC13_YEAST (59-206): 1.89e-37: 129: 47.30
+	Hs
		475485 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UBE2A_HUMAN (59-204): 1.17e-69: 210: 35.62
+	Hs
		475552 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27
+	Hs
		475597 UBC_HUMAN (1-153): 4.05e-53: 183: 99.35		UBE2B_HUMAN (59-204): 8.05e-69: 209: 36.30