HitPredict

Interactor 1: SYDE2 (Q5VT97)
Rho GTPase-activating protein SYDE2 (Synapse defective protein 1 homolog 2) (Protein syd-1 homolog 2)
Gene: SYDE2

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	32203420, unassigned2213
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 1025
+	Hs
		1068561 SYDE2_HUMAN (1-1194): 0: 1320: 100.00		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		1167422 RGAP1_HUMAN (529-1118): 3.07e-75: 264: 16.67		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		1153266 SYDE1_HUMAN (428-1188): 1.17e-98: 332: 36.25		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		1173151 SYDE1_HUMAN (428-1188): 1.17e-98: 332: 36.25		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		148770 MYO9B_HUMAN (301-1185): 3.97e-89: 320: 15.04		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		253366 SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		253410 SRGP2_HUMAN (397-1194): 2.33e-81: 291: 13.95		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		70674 MYO9A_HUMAN (296-1193): 1.72e-102: 360: 15.15		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		724864 RHG21_HUMAN (373-1189): 9.41e-95: 336: 17.25		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		149272 RGAP1_HUMAN (529-1118): 3.07e-75: 264: 16.67		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		1231295 RHG24_HUMAN (708-1192): 4.06e-72: 258: 18.95		OSBP2_HUMAN (273-623): 1.26e-32: 138: 15.11
+	Hs
		1068686 RHG23_HUMAN (384-1187): 2.4e-89: 319: 16.03		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		64621 RHG32_HUMAN (783-1026): 1.32e-54: 211: 27.53		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		724914 RHG24_HUMAN (708-1192): 4.06e-72: 258: 18.95		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		725200 RHG24_HUMAN (708-1192): 4.06e-72: 258: 18.95		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		63075 RHG42_HUMAN (690-1059): 4.21e-61: 228: 20.26		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96