HitPredict

Interactor 1: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	29162697, 28514442, 33961781, 35709258
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cnn_1N~Cnn_1N
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005813 - centrosome GO:0007098 - centrosome cycle
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2346 Hs			1 1893
+	Hs
		1138256 MYOME_HUMAN (1-2346): 0: 703: 100.00		MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47
+	Hs
		1302322 CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		828618 CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Mm
		823535 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		CTRO_MOUSE (160-640): 6.81e-12: 73.3: 16.37
+	Hs
		1034577 GOGB1_HUMAN (880-2332): 2.13e-37: 157: 10.38		GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50
+	Hs
		1034574 GOGA4_HUMAN (1116-2321): 1.5e-33: 145: 9.39		GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50
+	Hs
		1059212 GOGB1_HUMAN (880-2332): 2.13e-37: 157: 10.38		GOGB1_HUMAN (1-1241): 3.09e-44: 180: 9.91
+	Hs
		724994 CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		969580 CENPE_HUMAN (1-1839): 1.04e-60: 234: 11.33		CENPE_HUMAN (1-706): 6.04e-14: 80.3: 12.40
+	Hs
		528435 MYH4_HUMAN (1279-2334): 2.89e-32: 140: 9.95		MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98
+	Hs
		522657 MYH4_HUMAN (1279-2334): 2.89e-32: 140: 9.95		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77
+	Hs
		148769 GOGA4_HUMAN (1116-2321): 1.5e-33: 145: 9.39		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		502933 MYH4_HUMAN (1279-2334): 2.89e-32: 140: 9.95		MYH3_HUMAN (938-1610): 2.46e-10: 68.4: 9.82
+	Hs
		522585 MYH7_HUMAN (1-709): 1.93e-23: 111: 10.58		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77
+	Hs
		828575 CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69		CENPE_HUMAN (1-706): 6.04e-14: 80.3: 12.40
+	Hs
		148534 CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		528356 MYH6_HUMAN (1376-2333): 1.06e-22: 109: 8.98		MYH6_HUMAN (864-1654): 3.35e-11: 71.1: 11.49
+	Hs
		502901 MYH6_HUMAN (1376-2333): 1.06e-22: 109: 8.98		MYH3_HUMAN (938-1610): 2.46e-10: 68.4: 9.82