HitPredict

Interactor 1: F1711 (Q5VUB5)
Protein FAM171A1 (Astroprincin) (APCN)
Gene: FAM171A1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 1620
+	Hs
		666612 F1711_HUMAN (1-890): 0: 1330: 100.00		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		665615 F1711_HUMAN (1-890): 0: 1330: 100.00		EPHB2_HUMAN (938-1436): 2.19e-123: 416: 23.26
+	Hs
		665405 F1711_HUMAN (1-890): 0: 1330: 100.00		EPHA3_HUMAN (943-1427): 7.27e-120: 404: 25.87
+	Hs
		508056 F1711_HUMAN (1-890): 0: 1330: 100.00		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		435668 F1711_HUMAN (1-890): 0: 1330: 100.00		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		1083855 F1711_HUMAN (1-890): 0: 1330: 100.00		NTRK2_HUMAN (1093-1375): 7.35e-64: 236: 41.44
+	Hs
		384984 F1711_HUMAN (1-890): 0: 1330: 100.00		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1081506 F1711_HUMAN (1-890): 0: 1330: 100.00		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03
+	Hs
		601533 F171B_HUMAN (27-888): 0: 967: 31.41		FGFR2_HUMAN (952-1433): 9.52e-123: 407: 25.24
+	Hs
		68141 F1712_HUMAN (32-890): 0: 916: 38.37		EPHA3_HUMAN (943-1427): 7.27e-120: 404: 25.87
+	Hs
		68129 F1712_HUMAN (32-890): 0: 916: 38.37		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Mm
		546294 F171B_MOUSE (27-888): 0: 980: 32.12		NTRK2_MOUSE (1093-1379): 6.2e-64: 236: 41.22
+	Hs
		1083858 F171B_HUMAN (27-888): 0: 967: 31.41		NTRK2_HUMAN (1093-1375): 7.35e-64: 236: 41.44
+	Hs
		68174 F1712_HUMAN (32-890): 0: 916: 38.37		NTRK2_HUMAN (1093-1375): 7.35e-64: 236: 41.44
+	Hs
		68124 F1712_HUMAN (32-890): 0: 916: 38.37		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		68172 F1712_HUMAN (32-890): 0: 916: 38.37		NTRK3_HUMAN (1093-1375): 2.69e-59: 223: 39.03