Interactor 1: ARHGG (Q5VV41)
Rho guanine nucleotide exchange factor 16 (Ephexin-4)
Gene: ARHGEF16

Interactor 2: FGD6 (Q6ZV73)
FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24)
Gene: FGD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 32203420, unassigned2213
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PH, PH~RhoGEF, RhoGEF~RhoGEF, PH~SH3_1, RhoGEF~SH3_1
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0031267 - small GTPase binding
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 709
Hs

1 1430
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Last updated: 15 Jul 2024