HitPredict

Interactor 1: M9PAY7 (M9PAY7)
Pi3K21B, isoform C (Pi3K21B, isoform D)
Gene: Pi3K21B

Interactor 2: CSW (P29349)
Tyrosine-protein phosphatase corkscrew (EC 3.1.3.48)
Gene: CSW

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26839216, 27626673
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~SH2, SH2~Y_phosphatase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Dm			1 845
+	Hs
		412016 FYN_HUMAN (2-192): 1.28e-58: 193: 19.51		PTPRD_HUMAN (174-646): 5.55e-109: 370: 21.20
+	Hs
		522755 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTN1_HUMAN (363-734): 7.07e-119: 368: 23.89
+	Mm
		56907 FYN_MOUSE (2-192): 1.28e-58: 193: 19.51		PTPRF_MOUSE (174-646): 1.14e-106: 363: 20.80
+	Hs
		411959 FYN_HUMAN (2-192): 1.28e-58: 193: 19.51		PTPRF_HUMAN (174-646): 5.15e-106: 361: 20.80
+	Hs
		523222 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTN22_HUMAN (364-739): 8.18e-109: 354: 24.68
+	Rn
		1146020 SRC_RAT (2-192): 4.55e-59: 194: 18.41		Q66HJ7_RAT (162-654): 3.14e-106: 347: 20.84
+	Hs
		522756 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTPRA_HUMAN (162-654): 3.97e-106: 347: 20.65
+	Rn
		1144045 FYN_RAT (2-192): 1.28e-58: 193: 19.51		Q66HJ7_RAT (162-654): 3.14e-106: 347: 20.84
+	Mm
		403413 SRC_MOUSE (2-192): 6.89e-59: 194: 18.41		PTPRA_MOUSE (162-654): 8.49e-106: 346: 20.84
+	Hs
		411997 FYN_HUMAN (2-192): 1.28e-58: 193: 19.51		PTPRA_HUMAN (162-654): 3.97e-106: 347: 20.65
+	Mm
		574000 FYN_MOUSE (2-192): 1.28e-58: 193: 19.51		PTPRA_MOUSE (162-654): 8.49e-106: 346: 20.84
+	Rn
		976063 SRC_RAT (2-192): 4.55e-59: 194: 18.41		PTPRA_RAT (162-654): 1.13e-101: 334: 20.46
+	Hs
		433255 YES_HUMAN (2-192): 6.47e-60: 197: 17.91		PTPRE_HUMAN (162-654): 6.71e-95: 314: 20.15
+	Hs
		522754 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTN2_HUMAN (397-665): 1.79e-91: 296: 29.71
+	Hs
		441169 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTPRC_HUMAN (321-740): 5.47e-74: 265: 17.88
+	Hs
		411950 FYN_HUMAN (2-192): 1.28e-58: 193: 19.51		PTPRC_HUMAN (321-740): 5.47e-74: 265: 17.88
+	Rn
		94284 FYN_RAT (2-192): 1.28e-58: 193: 19.51		F1LXJ9_RAT (185-648): 2.07e-63: 234: 17.16
+	Hs
		522931 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTN11_HUMAN (1-291): 1.17e-65: 232: 62.18
+	Rn
		719284 FYN_RAT (2-192): 1.28e-58: 193: 19.51		PTN5_RAT (443-649): 4.44e-35: 139: 40.95
+	Hs
		522804 SRC_HUMAN (2-192): 6.32e-59: 194: 18.41		PTN6_HUMAN (3-369): 1.43e-17: 89.1: 15.23