HitPredict

Interactor 1: UBE2U (Q5VVX9)
Ubiquitin-conjugating enzyme E2 U (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme U) (Ubiquitin carrier protein U) (Ubiquitin-protein ligase U)
Gene: UBE2U

Interactor 2: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 321 Hs			1 259
+	Hs
		718404 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		PCGF2_HUMAN (30-255): 4.65e-59: 192: 35.57
+	Hs
		1138915 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05
+	Hs
		1138906 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1138931 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI35_HUMAN (34-257): 4.97e-35: 132: 16.13
+	Hs
		1138916 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI34_HUMAN (34-224): 1.74e-32: 125: 14.85
+	Hs
		1138920 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRIM5_HUMAN (34-224): 1.49e-31: 123: 16.20
+	Hs
		1138878 UBE2U_HUMAN (1-321): 7.67e-166: 465: 100.00		TRI68_HUMAN (32-225): 4.4e-31: 121: 12.68
+	Hs
		1304199 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1357712 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI35_HUMAN (34-257): 4.97e-35: 132: 16.13
+	Hs
		1290127 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		CHFR_HUMAN (7-166): 1.3e-33: 130: 20.25
+	Hs
		1336390 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI39_HUMAN (19-225): 2.05e-33: 128: 15.42
+	Hs
		1354526 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI10_HUMAN (32-224): 1.07e-33: 128: 14.41
+	Hs
		1318532 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI31_HUMAN (32-246): 2.35e-32: 124: 17.27
+	Hs
		1377469 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRI17_HUMAN (32-225): 4.02e-32: 124: 15.96
+	Hs
		1318719 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		TRIM5_HUMAN (34-224): 1.49e-31: 123: 16.20
+	Hs
		988038 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Mm
		919925 UB2D2_MOUSE (4-153): 8.78e-76: 230: 34.67		TRI17_MOUSE (32-225): 2.24e-31: 122: 15.02
+	Zm
		13425 B4FC97_MAIZE (4-153): 6.2e-76: 231: 31.33		A0A1D6FSN7_MAIZE (30-162): 4.47e-25: 105: 20.29
+	Hs
		1238409 UB2D4_HUMAN (4-153): 2.99e-76: 231: 31.33		DTX3_HUMAN (46-91): 2.96e-10: 61.7: 39.13
+	Hs
		282607 UB2D2_HUMAN (4-153): 8.78e-76: 230: 34.67		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04