HitPredict

Interactor 1: DAB2P (Q5VWQ8)
Disabled homolog 2-interacting protein (DAB2 interaction protein) (DAB2-interacting protein) (ASK-interacting protein 1) (AIP-1) (DOC-2/DAB-2 interactive protein)
Gene: DAB2IP

Interactor 2: ANS1A (Q92625)
Ankyrin repeat and SAM domain-containing protein 1A (Odin)
Gene: ANKS1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	32296183, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1189 Hs			1 1134
+	Hs
		1139204 DAB2P_HUMAN (1-1189): 0: 1081: 100.00		ANS1B_HUMAN (1-1101): 0: 593: 33.52
+	Hs
		1268491 SYGP1_HUMAN (20-1188): 0: 805: 46.82		ANS1A_HUMAN (1-1134): 0: 792: 100.00
+	Hs
		1115792 DAB2P_HUMAN (1-1189): 0: 1081: 100.00		Q49AR9_HUMAN (675-1134): 2.78e-116: 374: 92.70
+	Mm
		100037 SYGP1_MOUSE (20-1188): 0: 804: 47.09		ANS1B_MOUSE (1-1133): 0: 621: 33.57
+	Hs
		1191813 NGAP_HUMAN (42-1187): 0: 821: 55.65		ANS1B_HUMAN (1-1101): 0: 593: 33.52
+	Hs
		1299786 SYGP1_HUMAN (20-1188): 0: 805: 46.82		KDIS_HUMAN (121-538): 2.01e-56: 216: 15.20
+	Hs
		556720 SYGP1_HUMAN (20-1188): 0: 805: 46.82		ANK1_HUMAN (139-979): 1.84e-48: 191: 12.32
+	Hs
		965139 SYGP1_HUMAN (20-1188): 0: 805: 46.82		ANK2_HUMAN (180-837): 1.86e-34: 146: 13.55
+	Mm
		100050 SYGP1_MOUSE (20-1188): 0: 804: 47.09		ANK2_MOUSE (180-812): 1.69e-33: 143: 13.36
+	Hs
		1021395 IQGA2_HUMAN (246-763): 1.54e-106: 370: 14.87		ANK3_HUMAN (183-812): 9.9e-38: 157: 12.04
+	Hs
		1201452 IQGA3_HUMAN (246-745): 1.54e-98: 347: 13.05		Q9H4D1_HUMAN (60-245): 4.58e-19: 95.1: 38.17
+	Hs
		883552 IQGA3_HUMAN (246-745): 1.54e-98: 347: 13.05		RIPK4_HUMAN (60-245): 1.22e-18: 94: 37.63