HitPredict

Interactor 1: ECM29 (Q5VYK3)
Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog)
Gene: ECPAS

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z)
Gene: PSMB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1845 Hs			1 277
+	Hs
		656251 ECM29_HUMAN (1-1845): 0: 1279: 100.00		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67
+	Hs
		656731 ECM29_HUMAN (1-1845): 0: 1279: 100.00		PSB5_HUMAN (42-243): 1.28e-74: 230: 26.11
+	Hs
		656125 ECM29_HUMAN (1-1845): 0: 1279: 100.00		PSB9_HUMAN (42-227): 9.71e-21: 89.7: 29.41
+	Sc
		625930 ECM29_YEAST (4-1740): 0: 678: 22.25		PSB2_YEAST (11-272): 6.97e-82: 248: 54.92
+	Sc
		689177 ECM29_YEAST (4-1740): 0: 678: 22.25		PSA5_YEAST (13-253): 6.07e-77: 236: 20.62
+	Sc
		675414 ECM29_YEAST (4-1740): 0: 678: 22.25		PSB5_YEAST (5-246): 1.85e-70: 220: 22.54
+	Sc
		751158 ECM29_YEAST (4-1740): 0: 678: 22.25		PSB1_YEAST (43-222): 1.62e-26: 104: 32.04
+	Hs
		656268 CAND1_HUMAN (282-1301): 2.08e-34: 146: 12.77		PSA5_HUMAN (13-240): 3.35e-81: 246: 18.67