Interactor 1: RRAGB (Q5VZM2)
Ras-related GTP-binding protein B (Rag B) (RagB) (EC 3.6.5.-)
Gene: RRAGB

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.943

The method score is based on:

Property Details
Experiments 20381137, 25567906, 34079125, 33961781, 22980980, 25561175
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gtr1_RagA~LAMTOR
Common GO terms GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0008104 - protein localization
GO:0032008 - positive regulation of TOR signaling
GO:0051020 - GTPase binding
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 374
Hs

1 161
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024